A Dualistic Conformational Response to Substrate Binding in the Human Serotonin Transporter Reveals a High Affinity State for Serotonin

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

Atsuko Yamashita, Satinder K. Singh, Toshimitsu Kawate et al. · Nature · 2005 · 1.7K citations

Crystal Structure, Biochemistry, Natural Sciences +7

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

Sammanda Ramamoorthy, Andrea L. Bauman, Kimberly R. Moore et al. · Proceedings of the National Academy of Sciences · 1993 · 884 citations · Full text

Neurotransmitter, Psychopharmacology, Social Sciences +22

Cloning and expression of a functional serotonin transporter from rat brain

Randy Blakely, Haley E. Berson, Robert T. Fremeau et al. · Nature · 1991 · 835 citations · Full text

Neuropeptides, Functional Serotonin Transporter, Neurophysiology +14

X-ray structure of dopamine transporter elucidates antidepressant mechanism

Aravind Penmatsa, Kevin H. Wang, Eric Gouaux · Nature · 2013 · 628 citations · Full text

Biochemistry, Functional Selectivity, Dopamine Transporter +5

Cloning of a Serotonin Transporter Affected by Antidepressants

Beth J. Hoffman, Éva Mezey, Michael Brownstein · Science · 1991 · 610 citations