Steffen Sinning

Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning

Elizabeth K. Unger, Jacob P. Keller, Michael Altermatt et al. · Cell · 2020 · 179 citations · Full text

Machine Learning, Computational Neuroscience, Directed Evolution +4

Binding of Serotonin to the Human Serotonin Transporter. Molecular Modeling and Experimental Validation

Leyla Celik, Steffen Sinning, Kasper Severinsen et al. · Journal of the American Chemical Society · 2008 · 123 citations

Crystal Structure, Protein Assembly, Experimental Validation +20

Structural insights into the inhibition of glycine reuptake

Azadeh Shahsavar, Peter Stohler, Gleb Bourenkov et al. · Nature · 2021 · 106 citations

Biochemistry, G Protein-coupled Receptor, Glycine Reuptake +3

A direct interaction of cholesterol with the dopamine transporter prevents its out-to-inward transition

Talia Zeppelin, Lucy Kate Ladefoged, Steffen Sinning et al. · PLoS Computational Biology · 2018 · 100 citations · Full text

Binding and Orientation of Tricyclic Antidepressants within the Central Substrate Site of the Human Serotonin Transporter

Steffen Sinning, Maria Musgaard, Marie Jensen et al. · Journal of Biological Chemistry · 2009 · 95 citations · Full text