Concepedia
BMC Systems Biology · 2011 · 122 citations · 24 references
Open access
The TIGER package provides a consistent platform for algorithm development and extending existing genome-scale metabolic models with regulatory networks and high-throughput data.
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What is flux balance analysis?
Jeffrey D. Orth, Ines Thiele, Bernhard Ø. Palsson · Nature Biotechnology · 2010 · 4K citations
Material Flow Analysis, Environmental Monitoring, Engineering +5
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0
Jan Schellenberger, Richard Que, Ronan M. T. Fleming et al. · Nature Protocols · 2011 · 1.9K citations · Full text
Metabolic Network, Systems Biology, Engineering +13
Optknock: A bilevel programming framework for identifying gene knockout strategies for microbial strain optimization
Anthony P. Burgard, Priti Pharkya, Costas D. Maranas · Biotechnology and Bioengineering · 2003 · 1.3K citations
The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
Radhakrishnan Mahadevan, Christophe H. Schilling · Metabolic Engineering · 2003 · 1.2K citations
Biology, Metabolic Network, Engineering +12
Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox
Scott A. Becker, Adam M. Feist, Monica L. Mo et al. · Nature Protocols · 2007 · 796 citations
Metabolic Network, Engineering, Biochemistry +13