Concepedia

Enhanced Levels of CD154 (CD40 Ligand) on Platelets in Patients with Chronic Heart Failure

Christian Stumpf, Christoph Lehner, Saeed Eskafi, Dorette Raaz, Atilla Yılmaz, Susanne Ropers, Alexander Schmeißer, Joseph A. Ludwig, Werner G. Daniel, Christoph D. Garlichs

European Journal of Heart Failure · 2003 · 73 citations · 22 references

DOI

Abstract

Our pilot study demonstrates significantly enhanced levels of CD154 on platelets in patients with CHF. This suggests that the CD40-CD154 axis may contribute to the proinflammatory milieu, which exists in CHF and thus may play a pathogenic role in the development and progression of CHF.

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