Concepedia

Effects of Blood Pressure Lowering in Patients with Acute Ischemic Stroke and Carotid Artery Stenosis

Mirza Jusufovic, Else Charlotte Sandset, Philip M. Bath, Björn W. Karlson, Eivind Berge

International Journal of Stroke · 2014 · 37 citations · 29 references

Abstract

There is no clear evidence that the effect of candesartan is qualitatively different in patients with carotid artery stenosis, but there are signals that patients with severe stenosis are at particularly high risk of stroke progression and poor functional outcome.

References

29

Guidelines for the Early Management of Patients With Acute Ischemic Stroke

Edward C. Jauch, Jeffrey L. Saver, Harold P. Adams et al. · Stroke · 2013 · 7.6K citations · Full text

MRC European Carotid Surgery Trial: interim results for symptomatic patients with severe (70-99%) or with mild (0-29%) carotid stenosis

Charles Warlow · The Lancet · 1991 · 3.3K citations

Carotid Artery Surgery, Cardiovascular Disease, Symptomatic Patients +9

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack

The Lancet · 2001 · 3.2K citations

Hypertension, Cerebrovascular Disease, Perindopril-based Blood-pressure-lowering Regimen +17

Guidelines for Management of Ischaemic Stroke and Transient Ischaemic Attack 2008

Cerebrovascular Diseases · 2008 · 2.5K citations · Full text

Cerebrovascular Disease, Stroke Unit Service, Neurovascular Disease +23

North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress.

Stroke · 1991 · 1.1K citations · Full text

Patient Characteristics, Thrombosis, Medical Therapy +15