Comparative interactions of streptozotocin and chlorozotocin with DNA of an insulin-secreting cell line (RINr)

Fractionation of DNA from mammalian cells by alkaline elution

Kurt W. Kohn, Leonard C. Erickson, Regina A. G. Ewig et al. · Biochemistry · 1976 · 831 citations

Chromatin, Genome Instability, Dna +15

Handbook of Experimental Pharmacology, vol 14.

Aaron D. Freedman · Archives of Internal Medicine · 1972 · 777 citations

Molecular Pharmacology, Translational Pharmacology, Aldosterone Secretion +14

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

Hiroshi Yamamoto, Yasuko Uchigata, Hiroshi Okamoto · Nature · 1981 · 526 citations

Biosynthesis, Pancreatic Islets, Biochemistry +7

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.

Yasuko Uchigata, Hiroshi Yamamoto, Ayata Kawamura et al. · Journal of Biological Chemistry · 1982 · 250 citations · Full text

Reductive Stress, Insulin Signaling, Biosynthesis +14

Chemical carcinogenesis in the nervous system. Preferential accumulation of <i>O</i>6-methylguanine in rat brain deoxyribonucleic acid during repetitive administration of <i>N</i>-methyl-<i>N</i>-nitrosourea

G.P. Margison, Paul Kleihues · Biochemical Journal · 1975 · 203 citations · Full text

Pathology, Repetitive Administration, Glioma +16