An aptamer-based microfluidic device for thermally controlled affinity extraction

Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase

Craig Tuerk, Larry Gold · Science · 1990 · 10.2K citations

Exponential Enrichment, Bacteriophage, Molecular Biology +17

Aptamers: An Emerging Class of Molecules That Rival Antibodies in Diagnostics

Sumedha D. Jayasena · Clinical Chemistry · 1999 · 2.1K citations · Full text

Exponential Enrichment, Immunology, Molecular Biology +18

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

Pennina R. Langer, Alex A. Waldrop, David C. Ward · Proceedings of the National Academy of Sciences · 1981 · 1.1K citations · Full text

Bioorganic Chemistry, Engineering, Enzymatic Synthesis +17

Programmed Adsorption and Release of Proteins in a Microfluidic Device

Dale L. Huber, Ronald P. Manginell, Michael A. Samara et al. · Science · 2003 · 529 citations

Microfluidic Device, Engineering, Microfabrication +12

The biotin‐streptavidin interaction can be reversibly broken using water at elevated temperatures

Anders Holmberg, Anna Blomstergren, Olof Nord et al. · Electrophoresis · 2005 · 470 citations