Electrophoretic analysis of the unfolding of proteins by urea

Tissue sulfhydryl groups

George L. Ellman · Archives of Biochemistry and Biophysics · 1959 · 25.9K citations

Biochemistry, Glycobiology, Tissue Physiology +3

Protein denaturation. C. Theoretical models for the mechanism of denaturation.

Charles Tanford · PubMed · 1970 · 1.6K citations

Native State, Protein Chemistry, Biochemistry +14

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

Peter L. Privalov · Journal of Molecular Biology · 1974 · 1.4K citations

Protein Chemistry, Thermodynamic Approach, Biochemistry +9

The nature of the accessible and buried surfaces in proteins

Cyrus Chothia · Journal of Molecular Biology · 1976 · 1.2K citations

Protein Chemistry, Protein Secretion, Protein Assembly +11

Consideration of the possibility that the slow step in protein denaturation reactions is due to cis-trans isomerism of proline residues

John F. Brandts, Herbert R. Halvorson, Maureen Brennan · Biochemistry · 1975 · 1.1K citations