Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene

Alexander Poltorak, Xiaolong He, Irina Smirnova, +11

Science

A Toll-like receptor recognizes bacterial DNA

Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai, +8

Nature

Toll-like ReceptorsVirulence FactorPathogenesisInnate Immune SystemToll-like Receptor +5

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov, +1

Nature

InflammationToll-like ReceptorsMolecular ImmunologyCytokineAllergy +12

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Ruslan Medzhitov, Paula Preston‐Hurlburt, Charles A. Janeway

Nature

Host ResponseToll-like ReceptorsSignal TransductionAdaptive Immune SystemInnate Immune System +8

CD14, a Receptor for Complexes of Lipopolysaccharide (LPS) and LPS Binding Protein

Samuel D. Wright, Robert Ramos, Peter S. Tobias, +2

Science

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

Florian Heil, Hiroaki Hemmi, Hubertus Hochrein, +6

Science

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

Fumitaka Hayashi, Kelly D. Smith, Adrian Ozinsky, +7

Nature

Host ResponseToll-like ReceptorsBacterial FlagellinAutoimmune DiseaseVirulence Factor +9

Cell Activation and Apoptosis by Bacterial Lipoproteins Through Toll-like Receptor-2

Antonios O. Aliprantis, Ruey‐Bing Yang, Melanie R. Mark, +6

Science

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens

David M. Underhill, Adrian Ozinsky, Adeline M. Hajjar, +4

Nature

InflammationToll-like ReceptorsHost ResponsePathogenesisImmunology +7

TLR9 signals after translocating from the ER to CpG DNA in the lysosome

Eicke Latz, Annett Schoenemeyer, Alberto Visintin, +7

Nature Immunology

ChromatinCpg DnaSignal TransductionTlr9 SignalsNatural Sciences +8