Acute ketamine induces hippocampal synaptic depression and spatial memory impairment through dopamine D1/D5 receptors

Place navigation impaired in rats with hippocampal lesions

Richard Morris, Paul Garrud, J. N. P. Rawlins et al. · Nature · 1982 · 6.4K citations

Place Navigation, Neuroanatomy, Cortical Remodeling +6

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

John H. Krystal · Archives of General Psychiatry · 1994 · 3.3K citations

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

Bita Moghaddam, Barbara W. Adams, Anita Verma et al. · Journal of Neuroscience · 1997 · 1.8K citations · Full text

Neuropsychology, Prefrontal Cortex, Neurotransmitter +19

The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N‐methyl‐aspartate

Nabil A. Anis, Stephen C. Berry, N.R. Burton et al. · British Journal of Pharmacology · 1983 · 1.4K citations · Full text

Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory

Susheel Vijayraghavan, Min Wang, Shari G. Birnbaum et al. · Nature Neuroscience · 2007 · 1K citations

Cognitive Science, Brain Function, Prefrontal Neurons +11