Concepedia

Three-dimensional microwell arrays for cell culture

Christina L. Randall, Yevgeniy V. Kalinin, Mustapha Jamal, T.K. Ram Manohar, David H. Gracias

Lab on a Chip · 2010 · 65 citations · 19 references

DOI

Concepts

Abstract

We propose the concept of three-dimensional (3D) microwell arrays for cell culture applications and highlight the importance of oxygen diffusion through pores in all three dimensions to enhance cell viability.

References

19

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Microfluidic scaffolds for tissue engineering

Nakwon Choi, Mario Cabodi, Brittany Held et al. · Nature Materials · 2007 · 625 citations

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Probing the role of multicellular organization in three-dimensional microenvironments

Dirk R. Albrecht, Gregory H. Underhill, Travis Wassermann et al. · Nature Methods · 2006 · 548 citations

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Continuous perfusion microfluidic cell culture array for high‐throughput cell‐based assays

Paul J. Hung, Philip Lee, Poorya Sabounchi et al. · Biotechnology and Bioengineering · 2004 · 519 citations · Full text

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A practical guide to microfluidic perfusion culture of adherent mammalian cells

Lily Kim, Yi‐Chin Toh, Joel Voldman et al. · Lab on a Chip · 2007 · 453 citations

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