Synthesis of epibatidine homologues: Homoepibatidine and bis-homoepibatidine

Epibatidine: a novel (chloropyridyl)azabicycloheptane with potent analgesic activity from an Ecuadoran poison frog

Thomas F. Spande, H. Martin Garraffo, Michael W. Edwards et al. · Journal of the American Chemical Society · 1992 · 558 citations

Pharmaceutical Science, Potent Analgesic Activity, Altmetric Attention Score +18

A total synthesis of (±)-epibatidine

Simon C. Clayton, Andrew C. Regan · Tetrahedron Letters · 1993 · 122 citations

Bioorganic Chemistry, Total Synthesis, Pharmacology +2

Stereocontrolled total synthesis of (+)- and (-)-epibatidine

E. J. Corey, Teck‐Peng Loh, Achyutharao Sidduri et al. · The Journal of Organic Chemistry · 1993 · 95 citations

J. Corey, Chemical Measurement, Chemical Analysis +10

A versatile total synthesis of epibatidine and analogs

Dao Fei Huang, T. Y. Shen · Tetrahedron Letters · 1993 · 85 citations

Versatile Total Synthesis, Medicine, Pharmacology +3

The synthesis of (+)- and (–)-epibatidine

Stephen R. Fletcher, Raymond Baker, Mark S. Chambers et al. · Journal of the Chemical Society Chemical Communications · 1993 · 69 citations

Critical Step, Medicinal Chemistry, Enantioselective Synthesis +11