Zinc finger nuclease-mediated transgene deletion

GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion marker in higher plants.

Richard Jefferson, Tony A. Kavanagh, Michael Bevan · The EMBO Journal · 1987 · 9.9K citations · Full text

Biology, Plant Molecular Biology, Plant Genetics +12

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Jihye Cha, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2K citations · Full text

Genetics, Molecular Biology, Molecular Genetics +22

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Elena Pérez, Jianbin Wang, Jeffrey C. Miller et al. · Nature Biotechnology · 2008 · 996 citations

Viral Replication, Hiv-1 Resistance, Natural Sciences +12

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

Vipula K. Shukla, Yannick Doyon, Jeffrey C. Miller et al. · Nature · 2009 · 945 citations

Biology, Precise Genome Modification, Plant Genetics +9

High-frequency modification of plant genes using engineered zinc-finger nucleases

Jeffrey Townsend, David A. Wright, Ronnie J Winfrey et al. · Nature · 2009 · 732 citations · Full text

Plant Molecular Biology, Genetics, Genetic Engineering +4