The inflammatory response system and the availability of plasma tryptophan in patients with primary sleep disorders and major depression

Elevation of Plasma Cytokines in Disorders of Excessive Daytime Sleepiness: Role of Sleep Disturbance and Obesity

Alexandros N. Vgontzas, Dimitris A. Papanicolaou, Edward O. Bixler et al. · The Journal of Clinical Endocrinology & Metabolism · 1997 · 943 citations · Full text

Medicine, Immunology, Internal Medicine +12

The macrophage theory of depression

R.S. Smith · Medical Hypotheses · 1991 · 934 citations

Life Sciences, Immunology, Psychology +10

THE EFFECTS OF PSYCHOLOGICAL STRESS ON HUMANS: INCREASED PRODUCTION OF PRO-INFLAMMATORY CYTOKINES AND Th1-LIKE RESPONSE IN STRESS-INDUCED ANXIETY

Michaël Maes, Cai Song, Aihua Lin et al. · Cytokine · 1998 · 772 citations

Nursing, Immunology, Psychology +12

Increased plasma concentrations of interleukin-6, soluble interleukin-6, soluble interleukin-2 and transferrin receptor in major depression

Michaël Maes, Herbert Y. Meltzer, Eugène Bosmans et al. · Journal of Affective Disorders · 1995 · 629 citations

Nursing, Immunology, Psychiatry +14

Relationships between interleukin-6 activity, acute phase proteins, and function of the hypothalamic-pituitary-adrenal axis in severe depression

Michaël Maes, Simon Scharpé, Herbert Y. Meltzer et al. · Psychiatry Research · 1993 · 444 citations

Medicine, Endocrinology, Psychiatry +17