Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist

Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network

Angie L. Bookout, Yangsik Jeong, Michael Downes et al. · Cell · 2006 · 1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1999 · 937 citations

Life Sciences, Biochemistry, Pharmacology +14

ApoE Promotes the Proteolytic Degradation of Aβ

Qingguang Jiang, C.Y. Daniel Lee, Shweta Mandrekar et al. · Neuron · 2008 · 867 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Isoform-specific binding of apolipoprotein E to beta-amyloid.

Mary Jo LaDu, Michael T. Falduto, Arlene M. Manelli et al. · Journal of Biological Chemistry · 1994 · 536 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE

Suzanne E. Wahrle, Hong Jiang, Maia Parsadanian et al. · Journal of Biological Chemistry · 2004 · 474 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17