Concepedia

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344)

Ji Seon Park, Sang Dal Rhee, Nam Sook Kang, Won Hoon Jung, Hee Youn Kim, Jun Hyoung Kim, Seung Kyu Kang, Hyae Gyeong Cheon, Jin Hee Ahn, Ki Young Kim

Biochemical Pharmacology · 2011 · 40 citations · 22 references

DOI

Concepts

References

22

A Transgenic Model of Visceral Obesity and the Metabolic Syndrome

Hiroaki Masuzaki, J. Paterson, Hiroshi Shinyama et al. · Science · 2001 · 1.8K citations

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LigandFit: a novel method for the shape-directed rapid docking of ligands to protein active sites

C. M. Venkatachalam, Xiaoman Jiang, Tom Oldfield et al. · Journal of Molecular Graphics and Modelling · 2002 · 995 citations

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Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in <i>aP2</i> , the Adipocyte Fatty Acid Binding Protein

Gökhan S. Hotamışlıgil, Randall S. Johnson, R Distel et al. · Science · 1996 · 924 citations

, , +17

Induction of Peroxisome Proliferator-Activated Receptor γ during the Conversion of 3T3 Fibroblasts into Adipocytes Is Mediated by C/EBPβ, C/EBPδ, and Glucocorticoids

Zhidan Wu, Nancy L. R. Bucher, Stephen R. Farmer · Molecular and Cellular Biology · 1996 · 611 citations · Full text

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Novel Adipose Tissue–Mediated Resistance to Diet-Induced Visceral Obesity in 11β-Hydroxysteroid Dehydrogenase Type 1–Deficient Mice

Nicholas M. Morton, Janice M. Paterson, Hiroaki Masuzaki et al. · Diabetes · 2004 · 504 citations · Full text

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