Chemical and Pharmaceutical Bulletin · 1996 · 55 citations · 0 references
Life SciencesBiochemistryFood ScienceFood ChemistryStructure-activity RelationshipsAntioxidant DefenseBioactive Food ComponentsBioactive Natural ProductsFood AntioxidantsMedicinal PlantsStructure-activity Relationship AnalysisAntioxidant Natural ProductsAntioxidantsBioactive Plant CompoundsFruit AntioxidantsNatural AntioxidantsPhytochemical CompositionPlant Extract AntioxidantsPlant-derived Natural Products
Three novel antioxidative serotonin derivatives were isolated from safflower oil cake (Carthamus tinctorius L.). Their structures were established as 4, 4"-bis(N-p-coumaroyl)serotonin (1), 4-[N-(p-coumaroyl)serotonin-4"-yl]-N-feruloyserotonin (2), and 4, 4"-bis(N-feruloyl)serotonin (3). Antioxidative activities of the compounds were measured by ferric thiocyanate method and DPPH method, and the compounds showed strong antioxidative activity.