The therapeutic effect of TNFR1-selective antagonistic mutant TNF-α in murine hepatitis models

Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent

Joseph Keane, Sharon K. Gershon, Robert P. Wise et al. · New England Journal of Medicine · 2001 · 3.7K citations · Full text

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

Matthias Grell, Eleni Douni, Harald Wajant et al. · Cell · 1995 · 1.3K citations · Full text

Inflammation, Cytokine, Tumor Necrosis Factor +10

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

Joachim Rothe, Werner Lesslauer, Hansruedi Lötscher et al. · Nature · 1993 · 1.3K citations

Inflammation, Cytokine, Host Response +9

A T cell-dependent experimental liver injury in mice inducible by concanavalin A.

Gisa Tiegs, Julia Hentschel, Albrecht Wendel · Journal of Clinical Investigation · 1992 · 1.1K citations · Full text

Immunotoxicology, Immunology, Pathology +21

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

Bharat B. Aggarwal, Thomas E. Eessalu, Philip E. Hass · Nature · 1985 · 882 citations

Inflammation, Cytokine, Immune Regulation +9