Hiroko Shibata

The use of PVP as a polymeric carrier to improve the plasma half-life of drugs

Yoshihisa Kaneda, Yasuo Tsutsumi, Yasuo Yoshioka et al. · Biomaterials · 2003 · 188 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +13

Poly(<scp>l</scp>‐proline)‐binding proteins from chick embryos are a profilin and a profilactin

Masato Tanaka, Hiroko Shibata · European Journal of Biochemistry · 1985 · 176 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Creation and X-ray Structure Analysis of the Tumor Necrosis Factor Receptor-1-selective Mutant of a Tumor Necrosis Factor-α Antagonist

Hiroko Shibata, Yasuo Yoshioka, Akiko Ohkawa et al. · Journal of Biological Chemistry · 2007 · 96 citations · Full text

Life Sciences, Immunology, Pharmacology +14

Functionalization of Tumor Necrosis Factor-α Using Phage Display Technique and PEGylation Improves Its Antitumor Therapeutic Window

Hiroko Shibata, Yasuo Yoshioka, Shinji Ikemizu et al. · Clinical Cancer Research · 2004 · 76 citations

Medicine, Oncology, Pharmacology +13

Structure–Function Relationship of Tumor Necrosis Factor (TNF) and Its Receptor Interaction Based on 3D Structural Analysis of a Fully Active TNFR1-Selective TNF Mutant

Yohei Mukai, Hiroko Shibata, Teruya Nakamura et al. · Journal of Molecular Biology · 2008 · 68 citations

Life Sciences, Biochemistry, Molecular Biology +17