Application of the split-ubiquitin membrane yeast two-hybrid system to investigate membrane protein interactions

A novel genetic system to detect protein–protein interactions

Stanley Fields, Ok-kyu Song · Nature · 1989 · 6.1K citations

Interactomics, Natural Sciences, Protein Analysis +7

Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

Chang-Deng Hu, Tom K. Kerppola · Nature Biotechnology · 2003 · 781 citations · Full text

Living Cells, Immunocytochemical Technique, Engineering +13

Split ubiquitin as a sensor of protein interactions in vivo.

Nils Johnsson, Alexander Varshavsky · Proceedings of the National Academy of Sciences · 1994 · 781 citations

Protein Chemistry, Vivo Protein Interactions, Protein Function +13

A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins <i>in vivo</i>

Igor Štagljar, Chantal Korostensky, Nils Johnsson et al. · Proceedings of the National Academy of Sciences · 1998 · 593 citations

Protein Secretion, Protein Fusion, Molecular Biology +19

Distinctly regulated tandem upstream activation sites mediate catabolite repression of the CYC1 gene of S. cerevisiae

Leonard Guarente, Beth A. Lalonde, Paula Gifford et al. · Cell · 1984 · 481 citations

Transcriptional Regulation, Molecular Regulation, Genetics +10