Concepedia
Bioorganic & Medicinal Chemistry Letters · 2008 · 43 citations · 23 references
Open access
Molecular PharmacologyBiochemistryMedicineMechanism Of ActionNeuropharmacologyPharmacotherapyPharmacologyCarboxamido-substituted OpioidsOpioid Use Disorder
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Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction
Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations
Cent Inhibition, Inhibitory Activity, Biochemistry +8
Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes.
Vangala V. Subrahmanyam, A. B. Renwick, D. Gareth Walters et al. · PubMed · 2001 · 190 citations
Cytochrome P-450 Isoforms, Metabolomic Profiling, Molecular Biology +22
Bimorphinans as highly selective, potent .kappa. opioid receptor antagonists
Philip S. Portoghese, A. W. Lipkowski, A.E. Takemori · Journal of Medicinal Chemistry · 1987 · 113 citations
Molecular Pharmacology, Medicinal Chemistry, Potent .Kappa +11
Pentazocine.<sup>1</sup> Strong Analgesics and Analgesic Antagonists in the Benzomorphan Series<sup>2</sup>
S. A. Archer, Noel F. Albertson, Louis S. Harris et al. · Journal of Medicinal Chemistry · 1964 · 87 citations
Pain Medicine, Altmetric Attention Score, Pharmacotherapy +19
Design and Synthesis of Novel Dimeric Morphinan Ligands for κ and μ Opioid Receptors
John L. Neumeyer, Ao Zhang, Wennan Xiong et al. · Journal of Medicinal Chemistry · 2003 · 78 citations · Full text
Drug Target, Compound 17, Pharmacotherapy +17