Syntheses and opioid receptor binding properties of carboxamido-substituted opioids

References

Page 1

	Year	Citations
Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction Yung-Chi Cheng, William H. Prusoff Biochemical Pharmacology Cent InhibitionInhibitory ActivityBiochemistryMedicineEnzymatic Reaction	1973	12.8K
Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes. Vangala V. Subrahmanyam, A. B. Renwick, D. Gareth Walters, PubMed Cytochrome P-450 IsoformsMetabolomic ProfilingMolecular BiologyExperimental PharmacologyPharmacokinetics	2001	190
Bimorphinans as highly selective, potent .kappa. opioid receptor antagonists Philip S. Portoghese, A. W. Lipkowski, A.E. Takemori Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryPotent .KappaMedicineDrug Discovery	1987	113
Pentazocine.<sup>1</sup> Strong Analgesics and Analgesic Antagonists in the Benzomorphan Series<sup>2</sup> S. A. Archer, Noel F. Albertson, Louis S. Harris, Journal of Medicinal Chemistry Pain MedicineAltmetric Attention ScorePharmacotherapyExperimental PharmacologyPharmacodynamic Modeling	1964	87
Design and Synthesis of Novel Dimeric Morphinan Ligands for κ and μ Opioid Receptors John L. Neumeyer, Ao Zhang, Wennan Xiong, Journal of Medicinal Chemistry Drug TargetCompound 17PharmacotherapyChemistryμ Opioid Receptors	2003	78
Narcotic antagonists. 4. Carbon-6 derivatives of N-substituted noroxymorphones as narcotic antagonists Elliot F. Hahn, Jack Fishman, Richard D. Heilman Journal of Medicinal Chemistry	1975	75
N-[(Tetrahydrofuryl)alkyl] and N-(alkoxyalkyl) derivatives of (-)-normetazocine, compounds with differentiated opioid action profiles Herbert Merz, K Stockhaus Journal of Medicinal Chemistry Molecular PharmacologyMedicinal ChemistryDerivative (Chemistry)Pharmacological StudyDonut Icon	1979	70
Total synthesis and pharmacological activities of N-substituted 3,14-dihydroxymorphinans. I Ivo Monković, T. T. CONWAY, Harry S. Wong, Journal of the American Chemical Society Molecular PharmacologyDerivative (Chemistry)Bioorganic ChemistryBiochemistryDonut Icon	1973	63
Palladium-catalyzed cyanation of hindered, electron-rich aryl triflates by zinc cyanide Hitoshi Kubota, Kenner C. Rice Tetrahedron Letters Chemical EngineeringEngineeringOrganometallic CatalysisCatalysisChemistry	1998	60
Synthesis and Opioid Receptor Affinity of Morphinan and Benzomorphan Derivatives: Mixed κ Agonists and μ Agonists/Antagonists as Potential Pharmacotherapeutics for Cocaine Dependence John L. Neumeyer, Jean M. Bidlack, Rushi Zong, Journal of Medicinal Chemistry	1999	59

Page 1