Design, synthesis and identification of novel colchicine-derived immunosuppressant

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Jun S. Liu, Jesse D. Farmer, Willam S. Lane et al. · Cell · 1991 · 4.1K citations

Protein Function, Signal Transduction, Biochemistry +9

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

Robert E. Handschumacher, Matthew W. Harding, Jeffrey S. Rice et al. · Science · 1984 · 1.7K citations

CYCLOSPORIN A INITIALLY AS THE ONLY IMMUNOSUPPRESSANT IN 34 RECIPIENTS OF CADAVERIC ORGANS: 32 KIDNEYS, 2 PANCREASES, AND 2 LIVERS

R. Y. Calne, Keith Rolles, S Thiru et al. · The Lancet · 1979 · 1.1K citations

Hepatology, Autoimmune Disease, Kidney Transplant +12

SEROLOGICALLY DEFINED AND LYMPHOCYTE-DEFINED COMPONENTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX IN THE MOUSE

Fritz H. Bach, Michael B. Widmer, Marilyn L. Bach et al. · The Journal of Experimental Medicine · 1972 · 288 citations · Full text

Histocompatibility, Homograft Response, Immunogenetics +14

PROPERTIES OF THE PROTEIN SUBUNIT OF CENTRAL-PAIR AND OUTER-DOUBLET MICROTUBULES OF SEA URCHIN FLAGELLA

Michael L. Shelanski, Edwin W. Taylor · The Journal of Cell Biology · 1968 · 229 citations · Full text

Protein Assembly, Molecular Biology, Subunit Protein +16