Concepedia

Global Brain Gene Expression Analysis Links Glutamatergic and GABAergic Alterations to Suicide and Major Depression

Adolfo Sequeira, Firoza Mamdani, Carl Ernst, Marquis P. Vawter, William E. Bunney, Véronique Lebel, Sonia Rehal, Tim Klempan, Alain Gratton, Chawki Benkelfat,

PLoS ONE · 2009 · 391 citations · 75 references

DOI Full text

Open access

Abstract

The observed results represent the first overview of global expression changes in brains of suicide victims with and without major depression and suggest a global brain alteration of GLU and GABA receptor subunit genes in these conditions.

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