Concepedia

The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion

Ole Thastrup, Birthe Foder, Ole Scharff

Biochemical and Biophysical Research Communications · 1987 · 144 citations · 15 references

DOI

Concepts

References

15

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

Marco Castagna, Yoshimi Takai, Kozo Kaibuchi et al. · Journal of Biological Chemistry · 1982 · 4.8K citations · Full text

, , +16

Synergistic functions of protein phosphorylation and calcium mobilization in platelet activation.

Kozo Kaibuchi, Yoshimi Takai, Masanori Sawamura et al. · Journal of Biological Chemistry · 1983 · 703 citations · Full text

, , +17

Cytoplasmic free Ca<sup>2+</sup> in human platelets: Ca<sup>2+</sup> thresholds and Ca‐independent activation for shape‐change and secretion

T J Rink, S. W. Smith, Roger Y. Tsien · FEBS Letters · 1982 · 536 citations · Full text

, , +17

Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.

Kozo Kaibuchi, Terutaka Tsuda, Akira Kikuchi et al. · Journal of Biological Chemistry · 1986 · 241 citations · Full text

, , +17

Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.

H Lagast, Tullio Pozzan, F. A. Waldvogel et al. · Journal of Clinical Investigation · 1984 · 192 citations · Full text

, , +15