Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

Inflammation, Macrophage Biology, Cell Autophagy +11

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

Inflammation, Cytokine, Anti-inflammatory +8

PPARγ Is Required for Placental, Cardiac, and Adipose Tissue Development

Yaacov Barak, Michael C. Nelson, Estelita S. Ong et al. · Molecular Cell · 1999 · 1.9K citations · Full text

Metabolic Syndrome, Developmental Biology, Physiology +8

Oxidized LDL Regulates Macrophage Gene Expression through Ligand Activation of PPARγ

László Nagy, Peter Tontonoz, Jacqueline G. Alvarez et al. · Cell · 1998 · 1.9K citations · Full text

Inflammation, Ligand Activation, Signal Transduction +10