Biotechnology and Bioengineering · 1973 · 46 citations · 17 references
Life SciencesBiochemistryBiocatalysisEnzymologyReaction EngineeringEnzymatic CatalysisEnzyme KineticsEnzyme StabilityReactor DynamicsStability TheoryEnzyme Reactor KineticsMultiple Steady StatesOscillatory DynamicsOscillatory StabilityReactor StabilitySteady-state Kinetics
Abstract Several techniques for investigating the multiplicity and stability of open isothermal enzymatic reactors are discussed and some of the pitfalls in previous thinking pointed out. The example which is used to illustrate these methods exhibits several interesting features. Among these is the existence of a stable oscillatory state which surrounds a unique steady state which is asymptotically stable to certain finite disturbances.
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Instability and dynamic pattern in cellular networks
Hans G. Othmer, L. E. Scriven · Journal of Theoretical Biology · 1971 · 330 citations