Concepedia

Spatial and Temporal Analysis of NADPH Oxidase-Generated Hydrogen Peroxide Signals by Novel Fluorescent Reporter Proteins

Balázs Enyedi, Melinda Zana, Ágnes Donkó, Miklós Geiszt

Antioxidants and Redox Signaling · 2012 · 64 citations · 32 references

Abstract

Our results suggest that H2O2 produced by Noxs can induce redox changes in the intracellular milieu of Nox/Duox-expressing cells while simultaneously transmitting paracrine effects to neighboring cells.

References

32

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

Takeharu Nagai, Keiji Ibata, Eun Sun Park et al. · Nature Biotechnology · 2002 · 2.8K citations

Immunocytochemical Technique, Protein Expression, Protein Function +10

Genetically encoded fluorescent indicator for intracellular hydrogen peroxide

Vsevolod V. Belousov, Arkady F. Fradkov, Konstantin A. Lukyanov et al. · Nature Methods · 2006 · 1.2K citations

Redox Signaling, Biochemistry, Reporter Gene Assay +8

Unraveling the Biological Roles of Reactive Oxygen Species

Michael P. Murphy, Arne Holmgren, Nils‐Göran Larsson et al. · Cell Metabolism · 2011 · 809 citations · Full text

Inflammation, Biochemistry, Medicine +6

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

C C Winterbourn, Diana Metodiewa · Free Radical Biology and Medicine · 1999 · 790 citations

Bioorganic Chemistry, Biochemistry, Medicine +9

Free radicals and antioxidants – quo vadis?

Barry Halliwell · Trends in Pharmacological Sciences · 2011 · 692 citations

Medicine, Radical (Chemistry), Free Radicals +4