Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas

<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma

Monika E. Hegi, Annie‐Claire Diserens, Thierry Gorlia et al. · New England Journal of Medicine · 2005 · 7.3K citations · Full text

Medicine, Molecular Biology, Oncology +17

Response criteria for phase II studies of supratentorial malignant glioma.

David R. Macdonald, T L Cascino, S. Clifford Schold et al. · Journal of Clinical Oncology · 1990 · 2.4K citations

Medicine, Oncology, Radiology +17

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse

W.K. Alfred Yung, Robert E. Albright, Jeffrey J. Olson et al. · British Journal of Cancer · 2000 · 939 citations · Full text

Medicine, Oncology, Pharmacology +17

Multicenter Phase II Trial of Temozolomide in Patients With Anaplastic Astrocytoma or Anaplastic Oligoastrocytoma at First Relapse

W.K. Alfred Yung, Michael D. Prados, Ricardo Yayá et al. · Journal of Clinical Oncology · 1999 · 763 citations

Medicine, Oncology, Pharmacotherapy +17

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents.

Anthony E. Pegg · PubMed · 1990 · 738 citations

Medicine, Molecular Biology, Oncology +14