Concepedia

Valproic acid induces p21 and topoisomerase-II (α/β) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines

Chandra Das, Dolly Aguilera, Hernán Vásquez, Preethi Prasad, Ming Zhang, Johannes Wolff, Vidya Gopalakrishnan

Journal of Neuro-Oncology · 2007 · 104 citations · 33 references

DOI

Concepts

References

33

Histone deacetylase inhibition-mediated neuronal differentiation of multipotent adult neural progenitor cells

Jenny Hsieh, Kinichi Nakashima, Tomoko Kuwabara et al. · Proceedings of the National Academy of Sciences · 2004 · 722 citations · Full text

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Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

Melissa J. Peart, Gordon K. Smyth, Ryan K. van Laar et al. · Proceedings of the National Academy of Sciences · 2005 · 543 citations · Full text

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Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek et al. · PubMed · 2003 · 464 citations

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Linking the epigenetic ‘language’ of covalent histone modifications to cancer

Sandra B. Hake, Andrew Xiao, C. David Allis · British Journal of Cancer · 2004 · 387 citations · Full text

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Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy.

Rick Davis, David H. Peters, Donna McTavish · PubMed · 1994 · 294 citations

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