Gastrinomas Demonstrate Amplification of the HER-2/neu Proto-oncogene

Bret M. Evers, Peter L. Rady, Ken Sandoval, István Arany, Stephen K. Tyring, Ramón L. Sánchez, William H. Nealon, Courtney M. Townsend, James C. Thompson

Annals of Surgery · 1994 · 65 citations · 28 references

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Abstract

Amplification of the HER-2/neu gene, but not alterations of either p53 or ras, may be involved in the pathogenesis of gastrinomas. The unique PT cell line will be a useful model to further elucidate the molecular mechanisms that contribute to gastrinoma formation and growth.

References

28