The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

Malcolm Whitman, C. Peter Downes, Marilyn L. Keeler et al. · Nature · 1988 · 1K citations

Molecular Physiology, Signal Transduction, Novel Inositol Phospholipid +7

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

Kurt R. Auger, Leslie A. Serunian, Stephen P. Soltoff et al. · Cell · 1989 · 924 citations

Intact Cells, Signal Transduction, Developmental Biology +10

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

Malcolm Whitman, David R. Kaplan, Brian Schaffhausen et al. · Nature · 1985 · 825 citations

Signal Transduction, Signaling Pathway, Cell Regulation +9

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

David R. Kaplan, Malcolm Whitman, Brian Schaffhausen et al. · Cell · 1987 · 669 citations

Developmental Biology, Signal Transduction, Receptor Tyrosine Kinase +9

The colony stimulating factor-1 receptor associates with and activates phosphatidylinositol-3 kinase

Lyuba Varticovski, Brian Druker, Deborah K. Morrison et al. · Nature · 1989 · 327 citations

Factor-1 Receptor Associates, Signal Transduction, Signaling Pathway +11