Long-term Prospective Study of the Effect of Ursodeoxycholic Acid on Cystic Fibrosis-related Liver Disease

Abstract

Ursodeoxycholic acid is effective in improving cholestasis and hepatic dysfunction in nodular biliary cirrhosis and, also, in reversing the early sonography findings suggestive of focal biliary cirrhosis. It is speculated that ursodeoxycholic acid may prove to affect the natural history of cystic fibrosis-related liver disease.