Blockade by naloxone of cocaine-induced hyperactivity, reverse tolerance and conditioned place preference in mice

A psychomotor stimulant theory of addiction.

Roy A. Wise, Michael A. Bozarth · Psychological Review · 1987 · 2.7K citations

Neuropsychology, Substance Use, Behavioral Addiction +21

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

Alfred Mansour, Henry Khachaturian, M. E. Suzanne Lewis et al. · Pain · 1988 · 980 citations

Precise Localization, Pain Medicine, Pharmacotherapy +23

Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

G. Di Chiara, Assunta Impérato · Journal of Pharmacology and Experimental Therapeutics · 1988 · 921 citations

Extinction and recovery of cocaine self-administration following 6-hydroxydopamine lesions of the nucleus accumbens

David C. S. Roberts, George F. Koob, P. Klonoff et al. · Pharmacology Biochemistry and Behavior · 1980 · 726 citations

Substance Abuse, Behavioral Neuroscience, Neuroanatomy +14

Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats

Peter H. Kelly, Susan D. Iversen · European Journal of Pharmacology · 1976 · 713 citations

Psychoactive Drug, Selective 60Hda-induced Destruction, Behavioral Neuroscience +14