Random assignment in clinical trials: Issues in planning (Infant Health and Development Program)

Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial

Stuart Pocock, Richard Simon · Biometrics · 1975 · 2.4K citations

Public Health, Biostatistics, Clinical Epidemiology +12

Clinical Epidemiology: The Architecture of Clinical Research.

Annals of Internal Medicine · 1985 · 961 citations

Public Health, Clinical Sciences, Clinical Epidemiology +12

Forcing a sequential experiment to be balanced

Bradley Efron · Biometrika · 1971 · 852 citations

Public Health, Biostatistics, Experimental Design +13

The randomization and stratification of patients to clinical trials

Marvin Zelen · Journal of Chronic Diseases · 1974 · 614 citations

Public Health, Biostatistics, Clinical Sciences +10

Randomized Clinical Trials

David P. Byar, Richard Simon, William T. Friedewald et al. · New England Journal of Medicine · 1976 · 540 citations

Public Health, Biostatistics, Evidence-based Practice +15