The Synthesis of "C-O-N" Analogues of Nucleosides via the Mitsunobu Reaction

Abstract

A number of N-O-ribosides 5 were prepared by the reaction of appropriate cyclic N-hydroxycompounds 4 with three of the representative ribofuranose derivatives 3 in the presence of triphenylphosphine and diethyl azodicarboxylate as coupling agents.