Human Gαq: cDNA and tissue distribution

GTPase inhibiting mutations activate the α chain of Gs and stimulate adenylyl cyclase in human pituitary tumours

Claudia A. Landis, Susan B. Masters, Anna Spada et al. · Nature · 1989 · 1.4K citations

Life Sciences, Endocrinology, Molecular Biology +16

Two G Protein Oncogenes in Human Endocrine Tumors

John F. Lyons, Claudia A. Landis, Griffith Harsh et al. · Science · 1990 · 1K citations

Medicine, Genetics, Oncology +15

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

Stephen J. Taylor, Ho Zoon Chae, Sue Goo Rhee et al. · Nature · 1991 · 781 citations

Life Sciences, Biochemistry, Molecular Biology +8

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

Gabriel Berstein, Jonathan L. Blank, Alan V. Smrcka et al. · Journal of Biological Chemistry · 1992 · 344 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells.

Dong Wu, C H Lee, Sangkee Rhee et al. · Journal of Biological Chemistry · 1992 · 324 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14