Variations in the genes encoding the peroxisome proliferator-activated receptors ? and ? in psoriasis

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

Inflammation, Macrophage Biology, Cell Autophagy +11

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

Inflammation, Cytokine, Anti-inflammatory +8

The PPARα–leukotriene B4 pathway to inflammation control

Pallavi R. Devchand, H. J. Keller, Jeffrey M. Peters et al. · Nature · 1996 · 1.3K citations

Inflammation, Inflammatory Lung Disease, Immunology +5

A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity

Samir S. Deeb, Lluís Fajas, Masami Nemoto et al. · Nature Genetics · 1998 · 1.3K citations · Full text

Insulin Resistance, Metabolic Syndrome, Molecular Pharmacology +14

From Genotypes to Genes: Doubling the Sample Size

Peter Sasieni · Biometrics · 1997 · 902 citations

Genetic Testing, Unknown Allele, Genetics +19