Novel and potent tacrine-related hetero- and homobivalent ligands for acetylcholinesterase and butyrylcholinesterase

A new and rapid colorimetric determination of acetylcholinesterase activity

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Highly Potent, Selective, and Low Cost Bis-tetrahydroaminacrine Inhibitors of Acetylcholinesterase

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Differences in Active Site Gorge Dimensions of Cholinesterases Revealed by Binding of Inhibitors to Human Butyrylcholinesterase

Ashima Saxena, Ann M. G. Redman, Xuliang Jiang et al. · Biochemistry · 1997 · 247 citations

Bioorganic Chemistry, Molecular Biology, Active Site Gorge +16

Evaluation of short-tether Bis-THA AChE inhibitors. A further test of the dual binding site hypothesis

Paul R. Carlier, Yifan Han, Ella S.‐H. Chow et al. · Bioorganic & Medicinal Chemistry · 1999 · 156 citations · Full text

Drug Target, Further Test, Biochemistry +9

SAR of 9-Amino-1,2,3,4-tetrahydroacridine-Based Acetylcholinesterase Inhibitors:  Synthesis, Enzyme Inhibitory Activity, QSAR, and Structure-Based CoMFA of Tacrine Analogues

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