HIV Medicine · 2008 · 386 citations · 6 references
Public HealthHealth PolicyPharmacotherapyHiv ControlHiv PreventionReproductive HealthAntiretroviral TherapyGuideline ImplementationHiv Care ContinuumHuman Immunodeficiency Virus PharmacotherapyPost-exposure ProphylaxisPre-exposure ProphylaxisAntiretroviral AccessEarly Antiretroviral InitiationHiv Care AccessHiv Postexposure ProphylaxisHiv Pre-exposure ProphylaxisHiv Preexposure ProphylaxisPrimary InfectionVirological Diagnosis
European antiretroviral therapy practices vary widely across countries, influenced by drug registration, national policies, availability, reimbursement, and access, especially in Central and Eastern Europe. The guidelines aim to equip clinicians with updated recommendations to improve HIV care and promote a standardized standard of treatment across Europe. They revise the 2005 guidelines by incorporating current evidence on primary infection, treatment initiation, preferred initial regimens, virological failure management, and pregnancy care.
A working group of the European AIDS Clinical Society (EACS) have developed these guidelines for European clinicians to help them in the treatment of adults with HIV infection. This third version of the guidelines includes, as new topics, the assessment of patients at initial and subsequent clinic visits as well as post‐exposure prophylaxis. A revision of the 2005 guidelines based on current data includes changes in the sections on primary HIV infection, when to initiate therapy, which drug combinations are preferred as initial combination regimens for antiretroviral‐naïve patients, how to manage virological failure and the treatment of HIV during pregnancy. In Europe, there is a wide range of clinical practices in antiretroviral therapy depending on various factors such as drug registration, national policies, local availability, reimbursement and access to treatment. These can vary greatly from one country to another, especially in Central and Eastern parts of Europe. These guidelines are intended to help clinicians achieve the best care for their patients. In some countries, particularly where the quality of and access to care are not optimal, these guidelines should help AIDS societies and physicians or patient group organizations to negotiate with their national health authorities with a view to implementing what should be the standard of care for HIV‐infected patients all over Europe.
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Mauro Schechter, Regina Ferro do Lago, Aaron B. Mendelsohn et al. · JAIDS Journal of Acquired Immune Deficiency Syndromes · 2004 · 214 citations
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