A model study for the concise construction of the oxapentacyclic core of cortistatins through intramolecular Diels–Alder and oxidative dearomatization–cyclization reactions

Lianzhu Liu, Yingxiang Gao, Chao Che, Na Wu, David Zhigang Wang, Chuang‐Chuang Li, Zhen Yang

Chemical Communications · 2008 · 50 citations · 36 references

Concepts

Abstract

A unified strategy towards the facile construction of the [6.7.6.5] oxapentacyclic skeleton of cortistatins is reported, featuring intramolecular Diels-Alder (IMDA) and oxidative dearomatization-cyclization reactions as key steps.

References

36