Electroanalysis · 2001 · 55 citations · 25 references
EngineeringGlassy Carbon ElectrodeSelective DeterminationChemistryChemical EngineeringOrganic ElectrochemistryAnalytical Chemistryβ-Cyclodextrin Modified ElectrodeClinical ChemistryChemical SensorUric AcidChromatographyUrological ResearchPharmacologyElectrochemistryUa DeterminationUrologyCyclodextrin ProductionElectroanalytical SensorMedicineDrug Analysis
A β-cyclodextrin (CD) modified poly(N-acetylaniline) (PNAANI) glassy carbon electrode (GCE) was used to study the electrode reaction of uric acid (UA). The formation of a supramolecular complex between β-CD and UA improves the sensitivity and selectivity of the UA determination. The mechanism of selective detection of UA at the β-CD/PNAANI/GCE is proposed. Also, an analytical procedure involving square-wave voltammetry has been developed for determination of UA in the concentration range 1.0×10−5 to 2.0×10−4 mol dm−3.
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