Concepedia

Interferon-gamma produced by interleukin-12-activated tumor infiltrating CD8+T cells directly induces apoptosis of mouse hepatocellular carcinoma

Hideo Komita, Sadamu Homma, Hideo Saotome, Mikio Zeniya, Tsuneya Ohno, Gotaro Toda

Journal of Hepatology · 2006 · 51 citations · 33 references

DOI

Concepts

References

33

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

Michiko Kobayashi, Lori Fitz, Michael P. Ryan et al. · The Journal of Experimental Medicine · 1989 · 2K citations · Full text

, , +14

Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells.

Roberto Manetti, Paola Parronchi, M G Giudizi et al. · The Journal of Experimental Medicine · 1993 · 1.7K citations · Full text

, , +17

Antitumor and antimetastatic activity of interleukin 12 against murine tumors.

Michael J. Brunda, Leopoldo Luistro, Rajeev R. Warrier et al. · The Journal of Experimental Medicine · 1993 · 1.2K citations · Full text

, , +17

Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducers.

Susan Chan, B Perussia, Jean Gupta et al. · The Journal of Experimental Medicine · 1991 · 986 citations · Full text

, , +17

Recombinant IL-12 administration induces tumor regression in association with IFN- <i>gamma</i> production.

Chet Nastala, Howard Edington, T G McKinney et al. · The Journal of Immunology · 1994 · 792 citations · Full text

, , +17