Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

Melanie G. Lee, Paul Nurse · Nature · 1987 · 1.1K citations

Chromatin, Cell Division, Genetics +9

Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

Paul Russell, Paul Nurse · Cell · 1987 · 1K citations

Developmental Biology, Signal Transduction, Cell Division +12

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

Jean Gautier, Chris J. Norbury, Manfred J. Lohka et al. · Cell · 1988 · 876 citations

Transcriptional Regulation, Developmental Biology, Cell Regulation +10

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

William G. Dunphy, Leonardo Brizuela, David Beach et al. · Cell · 1988 · 825 citations

Xenopus Cdc2 Protein, Developmental Biology, Signal Transduction +10

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

Giulio Draetta, David Beach · Cell · 1988 · 791 citations

Cdc2 Protein Kinase, Cell Cycle-dependent Phosphorylation, Subunit Rearrangement +13