Concepedia

Targeting BCL-2 overexpression in various human malignancies through NF-κB inhibition by the proteasome inhibitor bortezomib

Bridget N. Fahy, Michael G. Schlieman, Melinda M. Mortenson, Subbulakshmi Virudachalam, Richard J. Bold

Cancer Chemotherapy and Pharmacology · 2005 · 125 citations · 36 references

DOI

Concepts

References

36

Activators and target genes of Rel/NF-κB transcription factors

Heike L. Pahl · Oncogene · 1999 · 3.7K citations

, , +14

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

Jialun Wang, Dongxiang Liu, Zhijia Zhang et al. · Proceedings of the National Academy of Sciences · 2000 · 1.2K citations

, , +17

Akt/Protein Kinase B Up-regulates Bcl-2 Expression through cAMP-response Element-binding Protein

Subbiah Pugazhenthi, Albina Nesterova, Carol L. Sable et al. · Journal of Biological Chemistry · 2000 · 801 citations · Full text

, , +15

Immunohistochemical analysis of bcl-2, bax, bcl-X, and mcl-1 expression in prostate cancers.

M Krajewska, S Krajewski, JI Epstein et al. · PubMed · 1996 · 596 citations

, , +16

bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis.

Frank A. Sinicrope, San Bao Ruan, Karen R. Cleary et al. · PubMed · 1995 · 581 citations

, , +17