Asymmetric Alkynylative Ring Opening Reaction of Oxabenzonorbornadienes Promoted by Palladium/Silver Cocatalytic System

Abstract

Abstract The combination of palladium(II) acetate/( R )‐xylyl‐Phanephos and silver triflate (Pd:Ag=1:1) was found to be an efficient catalytic system for the asymmetric ring opening reactions of oxabenzonorbornadienes with terminal alkynes. The products were typically afforded in good yields (up to 95% yield) and with high enantioselectivities (up to 99% ee ). magnified image