Synthesis of 2-Amino-4,6-diarylnicotinonitriles Using Silica-Bound N-Propyl Triethylenetetramine Sulfamic Acid as a Recyclable Solid Acid Catalyst

Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1

Toshiki Murata, Mitsuyuki Shimada, Sachiko Sakakibara et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 172 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

2-Amino-6-furan-2-yl-4-substituted Nicotinonitriles as A_2A Adenosine Receptor Antagonists

Monica Mantri, Olivier de Graaf, Jacobus van Veldhoven et al. · Journal of Medicinal Chemistry · 2008 · 147 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Silica-bonded S-sulfonic acid: an efficient and recyclable solid acid catalyst for the synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols)

Khodabakhsh Niknam, Dariush Saberi, Mohsen Sadegheyan et al. · Tetrahedron Letters · 2009 · 124 citations

Natural Sciences, Chemical Engineering, Chemistry +14

A novel and highly efficient method for the silylation of alcohols with hexamethyldisilazane (HMDS) catalyzed by recyclable sulfonic acid-functionalized ordered nanoporous silica

Daryoush Zareyee, Babak Karimi · Tetrahedron Letters · 2007 · 110 citations

Natural Sciences, Chemical Engineering, Chemistry +10

Structure−Activity Relationship Study of Prion Inhibition by 2-Aminopyridine-3,5-dicarbonitrile-Based Compounds:  Parallel Synthesis, Bioactivity, and in Vitro Pharmacokinetics

Barnaby C. H. May, Julie A. Zorn, Juanita Witkop et al. · Journal of Medicinal Chemistry · 2006 · 110 citations · Full text

Veterinary Medicine, Medicinal Chemistry, Pharmacokinetics +13