Increased P-glycoprotein expression and decreased phenobarbital distribution in the brain of pentylenetetrazole-kindled rats

Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy

Sanjay M. Sisodiya, W-R Lin, Brian Harding et al. · Brain · 2002 · 481 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Overexpression of Multiple Drug Resistance Genes in Endothelial Cells from Patients with Refractory Epilepsy

Stephen M. Dombrowski, Shailesh Y. Desai, Matteo Marroni et al. · Epilepsia · 2001 · 428 citations · Full text

Medicine, Neuroscience, Pharmacology +13

Cyclosporin A Is a Broad-Spectrum Multidrug Resistance Modulator

Misbah Qadir, Kieran L. O’Loughlin, Stacy M. Fricke et al. · Clinical Cancer Research · 2005 · 238 citations · Full text

Medicine, Oncology, Pharmacology +16

Multidrug Resistance Protein MRP2 Contributes to Blood-Brain Barrier Function and Restricts Antiepileptic Drug Activity

Heidrun Potschka, Maren Fedrowitz, Wolfgang Löscher · Journal of Pharmacology and Experimental Therapeutics · 2003 · 235 citations

Medicine, Neuroscience, Pharmacology +17

P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood–brain barrier: evidence from microdialysis experiments in rats

Heidrun Potschka, Maren Fedrowitz, Wolfgang Löscher · Neuroscience Letters · 2002 · 230 citations

Medicine, Pharmacokinetics, Pharmacology +15