Ugibohlin: A New Dibromo-seco-isophakellin from <i>Axinella </i><i>carteri</i>

Abstract

Chemical investigation of a marine sponge, Axinella carteri, collected on a reed slope of Talakanen Island, Phillipines, has afforded the new metabolite ugibohlin (1), along with its known cyclic derivative dibromoisophakellin (2). Structure elucidation of the isolated metabolites involved high-field 2D NMR spectroscopy including (1)H-(1)H COSY, HSQC, and HMBC. Revised chemical shift assignments are provided for 2.