Publication | Open Access
Russuphelin A, a New Cytotoxic Substance from the Mushroom Russula subnigricans Hongo.
32
Citations
0
References
1992
Year
Medicinal ChemistryNew Cytotoxic SubstanceBioorganic ChemistryBiochemistryRussuphelin AMedicineNatural SciencesBioassay-guided IsolationPathologySecondary MetaboliteTotal SynthesisMedicinal FungiToxicologyPhytochemistryPharmacologyDrug DiscoveryMushroom Russula
A new cytotoxic substance, designated russuphelin A (1), has been isolated from the mushroom Russula subnigricans Hongo (Basidiomycetes). The structure was elucidated as 2,6-bis(2,6-dichloro-4-hydroxyphenyloxy)-1,4-dimethoxy-benzene on the basis of spectroscopic data and confirmed by total synthesis.