Hyperpolarized Amino Acids for In Vivo Assays of Transaminase Activity

Abstract

Novel markers: NMR spectroscopy has a unique potential to monitor chemical reactions in vivo (see figure). Unlike other imaging techniques, non-invasive NMR experiments yield information on the chemical nature of educts and products through their chemical shifts. The hyperpolarization of amino acids for in vivo assays of transaminase activity is shown. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.